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Development of a Capsule Robot for Exploring the Colon

A tether-less inchworm-like capsule robot (ILCR) is promising to enable a non-invasive exploration of the colon, while existing ILCRs show barely satisfactory movement performance because the colon environment is nonstructural. In this current study, we develop an enhanced ILCR based on a design rul...

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Detalles Bibliográficos
Autores principales: Gao, Jinyang, Zhang, Zenglei, Yan, Guozheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680549/
https://www.ncbi.nlm.nih.gov/pubmed/31284610
http://dx.doi.org/10.3390/mi10070456
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author Gao, Jinyang
Zhang, Zenglei
Yan, Guozheng
author_facet Gao, Jinyang
Zhang, Zenglei
Yan, Guozheng
author_sort Gao, Jinyang
collection PubMed
description A tether-less inchworm-like capsule robot (ILCR) is promising to enable a non-invasive exploration of the colon, while existing ILCRs show barely satisfactory movement performance because the colon environment is nonstructural. In this current study, we develop an enhanced ILCR based on a design rule of maximizing the achievable periodic stroke and minimizing the body length, with the aim of improving movement performance. By designing an axial compact expanding mechanism (EM), employing a novel linear mechanism (LM), and integrating a hollow-cylinder-like power source based on wireless power transmission (WPT), the enhanced ILCR achieves a periodic stroke of 38 mm within a small body length of 33 mm. Our experiments show that the EM and LM can work reliably in an ex-vivo colon with a lot of intestinal mucus, and the power source can safely supply a stable working voltage of 3.3 V even in the worst case. Being wirelessly controlled and powered, the enhanced ILCR shows satisfactory movement performance, with velocities of 15.8 cm/min, 12.1 cm/min, and 7.4 cm/min in a transparent tube, a tiled colon, and a suspended colon, respectively, promising to accomplish an exploration for the 1.5-m long colon within 30 min.
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spelling pubmed-66805492019-08-09 Development of a Capsule Robot for Exploring the Colon Gao, Jinyang Zhang, Zenglei Yan, Guozheng Micromachines (Basel) Article A tether-less inchworm-like capsule robot (ILCR) is promising to enable a non-invasive exploration of the colon, while existing ILCRs show barely satisfactory movement performance because the colon environment is nonstructural. In this current study, we develop an enhanced ILCR based on a design rule of maximizing the achievable periodic stroke and minimizing the body length, with the aim of improving movement performance. By designing an axial compact expanding mechanism (EM), employing a novel linear mechanism (LM), and integrating a hollow-cylinder-like power source based on wireless power transmission (WPT), the enhanced ILCR achieves a periodic stroke of 38 mm within a small body length of 33 mm. Our experiments show that the EM and LM can work reliably in an ex-vivo colon with a lot of intestinal mucus, and the power source can safely supply a stable working voltage of 3.3 V even in the worst case. Being wirelessly controlled and powered, the enhanced ILCR shows satisfactory movement performance, with velocities of 15.8 cm/min, 12.1 cm/min, and 7.4 cm/min in a transparent tube, a tiled colon, and a suspended colon, respectively, promising to accomplish an exploration for the 1.5-m long colon within 30 min. MDPI 2019-07-06 /pmc/articles/PMC6680549/ /pubmed/31284610 http://dx.doi.org/10.3390/mi10070456 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gao, Jinyang
Zhang, Zenglei
Yan, Guozheng
Development of a Capsule Robot for Exploring the Colon
title Development of a Capsule Robot for Exploring the Colon
title_full Development of a Capsule Robot for Exploring the Colon
title_fullStr Development of a Capsule Robot for Exploring the Colon
title_full_unstemmed Development of a Capsule Robot for Exploring the Colon
title_short Development of a Capsule Robot for Exploring the Colon
title_sort development of a capsule robot for exploring the colon
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680549/
https://www.ncbi.nlm.nih.gov/pubmed/31284610
http://dx.doi.org/10.3390/mi10070456
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