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Development of a Capsule Robot for Exploring the Colon
A tether-less inchworm-like capsule robot (ILCR) is promising to enable a non-invasive exploration of the colon, while existing ILCRs show barely satisfactory movement performance because the colon environment is nonstructural. In this current study, we develop an enhanced ILCR based on a design rul...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680549/ https://www.ncbi.nlm.nih.gov/pubmed/31284610 http://dx.doi.org/10.3390/mi10070456 |
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author | Gao, Jinyang Zhang, Zenglei Yan, Guozheng |
author_facet | Gao, Jinyang Zhang, Zenglei Yan, Guozheng |
author_sort | Gao, Jinyang |
collection | PubMed |
description | A tether-less inchworm-like capsule robot (ILCR) is promising to enable a non-invasive exploration of the colon, while existing ILCRs show barely satisfactory movement performance because the colon environment is nonstructural. In this current study, we develop an enhanced ILCR based on a design rule of maximizing the achievable periodic stroke and minimizing the body length, with the aim of improving movement performance. By designing an axial compact expanding mechanism (EM), employing a novel linear mechanism (LM), and integrating a hollow-cylinder-like power source based on wireless power transmission (WPT), the enhanced ILCR achieves a periodic stroke of 38 mm within a small body length of 33 mm. Our experiments show that the EM and LM can work reliably in an ex-vivo colon with a lot of intestinal mucus, and the power source can safely supply a stable working voltage of 3.3 V even in the worst case. Being wirelessly controlled and powered, the enhanced ILCR shows satisfactory movement performance, with velocities of 15.8 cm/min, 12.1 cm/min, and 7.4 cm/min in a transparent tube, a tiled colon, and a suspended colon, respectively, promising to accomplish an exploration for the 1.5-m long colon within 30 min. |
format | Online Article Text |
id | pubmed-6680549 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-66805492019-08-09 Development of a Capsule Robot for Exploring the Colon Gao, Jinyang Zhang, Zenglei Yan, Guozheng Micromachines (Basel) Article A tether-less inchworm-like capsule robot (ILCR) is promising to enable a non-invasive exploration of the colon, while existing ILCRs show barely satisfactory movement performance because the colon environment is nonstructural. In this current study, we develop an enhanced ILCR based on a design rule of maximizing the achievable periodic stroke and minimizing the body length, with the aim of improving movement performance. By designing an axial compact expanding mechanism (EM), employing a novel linear mechanism (LM), and integrating a hollow-cylinder-like power source based on wireless power transmission (WPT), the enhanced ILCR achieves a periodic stroke of 38 mm within a small body length of 33 mm. Our experiments show that the EM and LM can work reliably in an ex-vivo colon with a lot of intestinal mucus, and the power source can safely supply a stable working voltage of 3.3 V even in the worst case. Being wirelessly controlled and powered, the enhanced ILCR shows satisfactory movement performance, with velocities of 15.8 cm/min, 12.1 cm/min, and 7.4 cm/min in a transparent tube, a tiled colon, and a suspended colon, respectively, promising to accomplish an exploration for the 1.5-m long colon within 30 min. MDPI 2019-07-06 /pmc/articles/PMC6680549/ /pubmed/31284610 http://dx.doi.org/10.3390/mi10070456 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Gao, Jinyang Zhang, Zenglei Yan, Guozheng Development of a Capsule Robot for Exploring the Colon |
title | Development of a Capsule Robot for Exploring the Colon |
title_full | Development of a Capsule Robot for Exploring the Colon |
title_fullStr | Development of a Capsule Robot for Exploring the Colon |
title_full_unstemmed | Development of a Capsule Robot for Exploring the Colon |
title_short | Development of a Capsule Robot for Exploring the Colon |
title_sort | development of a capsule robot for exploring the colon |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680549/ https://www.ncbi.nlm.nih.gov/pubmed/31284610 http://dx.doi.org/10.3390/mi10070456 |
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