Evolution from Covalent to Self-Assembled PAMAM-Based Dendrimers as Nanovectors for siRNA Delivery in Cancer by Coupled In Silico-Experimental Studies. Part I: Covalent siRNA Nanocarriers

Small interfering RNAs (siRNAs) represent a new approach towards the inhibition of gene expression; as such, they have rapidly emerged as promising therapeutics for a plethora of important human pathologies including cancer, cardiovascular diseases, and other disorders of a genetic etiology. However...

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Detalles Bibliográficos
Autores principales: Marson, Domenico, Laurini, Erik, Aulic, Suzana, Fermeglia, Maurizio, Pricl, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680565/
https://www.ncbi.nlm.nih.gov/pubmed/31323863
http://dx.doi.org/10.3390/pharmaceutics11070351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680565/
https://www.ncbi.nlm.nih.gov/pubmed/31323863
http://dx.doi.org/10.3390/pharmaceutics11070351

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