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Vitamin E-Loaded PLA- and PLGA-Based Core-Shell Nanoparticles: Synthesis, Structure Optimization and Controlled Drug Release

The (±)-α-Tocopherol (TP) with vitamin E activity has been encapsulated into biocompatible poly(lactic acid) (PLA) and poly(lactide-co-glycolide) (PLGA) carriers, which results in the formation of well-defined nanosized (d ~200–220 nm) core-shell structured particles (NPs) with 15–19% of drug loadin...

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Detalles Bibliográficos
Autores principales: Varga, Norbert, Turcsányi, Árpád, Hornok, Viktória, Csapó, Edit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680571/
https://www.ncbi.nlm.nih.gov/pubmed/31336591
http://dx.doi.org/10.3390/pharmaceutics11070357