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Structural and Biological Investigations for a Series of N-5 Substituted Pyrrolo[3,2-d]pyrimidines as Potential Anti-Cancer Therapeutics

Pyrrolo[3,2-d]pyrimidines have been studied for many years as potential lead compounds for the development of antiproliferative agents. Much of the focus has been on modifications to the pyrimidine ring, with enzymatic recognition often modulated by C2 and C4 substituents. In contrast, this work foc...

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Detalles Bibliográficos
Autores principales: Cawrse, Brian M., Robinson, Nia’mani M., Lee, Nina C., Wilson, Gerald M., Seley-Radtke, Katherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680647/
https://www.ncbi.nlm.nih.gov/pubmed/31340431
http://dx.doi.org/10.3390/molecules24142656