Effect of Ticagrelor, a Cytochrome P450 3A4 Inhibitor, on the Pharmacokinetics of Tadalafil in Rats

Tadalafil is a cytochrome P450 (CYP) 3A4 substrate. Because there are few data on drug-drug interactions, it is advisable to take sufficient consideration when co-administering tadalafil with CYP3A4 inducers or inhibitors. This study was conducted to assess the effect of ticagrelor, a CYP3A4 inhibit...

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Detalles Bibliográficos
Autores principales: Na, Young-Guk, Byeon, Jin-Ju, Huh, Hyun Wook, Kim, Min-Ki, Shin, Young G., Lee, Hong-Ki, Cho, Cheong-Weon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680770/
https://www.ncbi.nlm.nih.gov/pubmed/31330787
http://dx.doi.org/10.3390/pharmaceutics11070354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680770/
https://www.ncbi.nlm.nih.gov/pubmed/31330787
http://dx.doi.org/10.3390/pharmaceutics11070354

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