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Evolution from Covalent to Self-Assembled PAMAM-Based Dendrimers as Nanovectors for siRNA Delivery in Cancer by Coupled in Silico-Experimental Studies. Part II: Self-Assembled siRNA Nanocarriers

In part I of this review, the authors showed how poly(amidoamine) (PAMAM)-based dendrimers can be considered as promising delivering platforms for siRNA therapeutics. This is by virtue of their precise and unique multivalent molecular architecture, characterized by uniform branching units and a plet...

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Detalles Bibliográficos
Autores principales: Laurini, Erik, Marson, Domenico, Aulic, Suzana, Fermeglia, Maurizio, Pricl, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680776/
https://www.ncbi.nlm.nih.gov/pubmed/31295912
http://dx.doi.org/10.3390/pharmaceutics11070324