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Enhanced Intradermal Delivery of Nanosuspensions of Antifilariasis Drugs Using Dissolving Microneedles: A Proof of Concept Study

Conventional oral administration of antifilariasis drugs results in nonspecific targeting of the drugs and the intradermal delivery of nanoparticles with sizes of <100 nm could be used to improve lymphatic uptake. This study investigated the combination of nanosuspension and dissolving microneedl...

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Detalles Bibliográficos
Autores principales: Permana, Andi Dian, McCrudden, Maelíosa T. C., Donnelly, Ryan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680801/
https://www.ncbi.nlm.nih.gov/pubmed/31319602
http://dx.doi.org/10.3390/pharmaceutics11070346