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Enhanced Intradermal Delivery of Nanosuspensions of Antifilariasis Drugs Using Dissolving Microneedles: A Proof of Concept Study
Conventional oral administration of antifilariasis drugs results in nonspecific targeting of the drugs and the intradermal delivery of nanoparticles with sizes of <100 nm could be used to improve lymphatic uptake. This study investigated the combination of nanosuspension and dissolving microneedl...
Autores principales: | Permana, Andi Dian, McCrudden, Maelíosa T. C., Donnelly, Ryan F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680801/ https://www.ncbi.nlm.nih.gov/pubmed/31319602 http://dx.doi.org/10.3390/pharmaceutics11070346 |
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