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Anticancer Function and ROS-Mediated Multi-Targeting Anticancer Mechanisms of Copper (II) 2-hydroxy-1-naphthaldehyde Complexes

Multi-targeting of oncoproteins by a single molecule represents an effectual, rational, and an alternative approach to target therapy. We carried out a systematic study to reveal the mechanisms of action of newly synthesized Cu(2+) compounds of 2-naphthalenol and 1-(((2-pyridinylmethyl)imino)methyl)...

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Detalles Bibliográficos
Autores principales: Khan, Muhammad Hamid, Cai, Meiling, Deng, Jungang, Yu, Ping, Liang, Hong, Yang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680819/
https://www.ncbi.nlm.nih.gov/pubmed/31336900
http://dx.doi.org/10.3390/molecules24142544