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Tissue-Specific Sample Dilution: An Important Parameter to Optimise Prior to Untargeted LC-MS Metabolomics

When developing a sample preparation protocol for LC–MS untargeted metabolomics of a new sample matrix unfamiliar to the laboratory, selection of a suitable injection concentration is rarely described. Here we developed a simple workflow to address this issue prior to untargeted LC–MS metabolomics u...

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Detalles Bibliográficos
Autores principales: Wu, Zhanxuan E., Kruger, Marlena C., Cooper, Garth J.S., Poppitt, Sally D., Fraser, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680868/
https://www.ncbi.nlm.nih.gov/pubmed/31252691
http://dx.doi.org/10.3390/metabo9070124