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Withanolides, Extracted from Datura Metel L. Inhibit Keratinocyte Proliferation and Imiquimod-Induced Psoriasis-Like Dermatitis via the STAT3/P38/ERK1/2 Pathway

Psoriasis is an immune-mediated inflammatory dermatosis characterized by epidermal hyperplasia and excessive infiltration of inflammatory cells. Withanolides, extracted from Datura metel L.; are the main effective components for the treatment of psoriasis. However, the precise mechanisms of action o...

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Detalles Bibliográficos
Autores principales: Li, Tingting, Wei, Zheng, Sun, Yanping, Wang, Qiuhong, Kuang, Haixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680890/
https://www.ncbi.nlm.nih.gov/pubmed/31319488
http://dx.doi.org/10.3390/molecules24142596