Cargando…
Withanolides, Extracted from Datura Metel L. Inhibit Keratinocyte Proliferation and Imiquimod-Induced Psoriasis-Like Dermatitis via the STAT3/P38/ERK1/2 Pathway
Psoriasis is an immune-mediated inflammatory dermatosis characterized by epidermal hyperplasia and excessive infiltration of inflammatory cells. Withanolides, extracted from Datura metel L.; are the main effective components for the treatment of psoriasis. However, the precise mechanisms of action o...
Autores principales: | Li, Tingting, Wei, Zheng, Sun, Yanping, Wang, Qiuhong, Kuang, Haixue |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680890/ https://www.ncbi.nlm.nih.gov/pubmed/31319488 http://dx.doi.org/10.3390/molecules24142596 |
Ejemplares similares
-
Five Withanolides from the Leaves of Datura metel L. and Their Inhibitory Effects on Nitric Oxide Production
por: Yang, Bing-You, et al.
Publicado: (2014) -
UPLC-MS/MS Identification and Quantification of Withanolides from Six Parts of the Medicinal Plant Datura Metel L.
por: Yang, Shi Hui, et al.
Publicado: (2020) -
Datura Metel L. Ameliorates Imiquimod-Induced Psoriasis-Like Dermatitis and Inhibits Inflammatory Cytokines Production through TLR7/8–MyD88–NF-κB–NLRP3 Inflammasome Pathway
por: Yang, Bing-You, et al.
Publicado: (2019) -
Two New Withanolide Lactones from Flos Daturae
por: Kuang, Hai-Xue, et al.
Publicado: (2011) -
ANTIOXIDANT ACTIVITY AND FT-IR ANALYSIS OF DATURA INNOXIA AND DATURA METEL LEAF AND SEED METHANOLIC EXTRACTS
por: Bhardwaj, Khushboo, et al.
Publicado: (2016)