Comparable Bioavailability and Disposition of Pefloxacin in Patients with Cystic Fibrosis and Healthy Volunteers Assessed via Population Pharmacokinetics

Quinolone antibiotics present an attractive oral treatment option in patients with cystic fibrosis (CF). Prior studies have reported comparable clearances and volumes of distribution in patients with CF and healthy volunteers for primarily renally cleared quinolones. We aimed to provide the first ph...

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Detalles Bibliográficos
Autores principales: Bulitta, Jürgen B., Jiao, Yuanyuan, Landersdorfer, Cornelia B., Sutaria, Dhruvitkumar S., Tao, Xun, Shin, Eunjeong, Höhl, Rainer, Holzgrabe, Ulrike, Stephan, Ulrich, Sörgel, Fritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681055/
https://www.ncbi.nlm.nih.gov/pubmed/31295857
http://dx.doi.org/10.3390/pharmaceutics11070323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681055/
https://www.ncbi.nlm.nih.gov/pubmed/31295857
http://dx.doi.org/10.3390/pharmaceutics11070323

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