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Identification of Catalposide Metabolites in Human Liver and Intestinal Preparations and Characterization of the Relevant Sulfotransferase, UDP-glucuronosyltransferase, and Carboxylesterase Enzymes

Catalposide, an active component of Veronica species such as Catalpa ovata and Pseudolysimachion lingifolium, exhibits anti-inflammatory, antinociceptic, anti-oxidant, hepatoprotective, and cytostatic activities. We characterized the in vitro metabolic pathways of catalposide to predict its pharmaco...

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Detalles Bibliográficos
Autores principales: Hwang, Deok-Kyu, Kim, Ju-Hyun, Shin, Yongho, Choi, Won-Gu, Kim, Sunjoo, Cho, Yong-Yeon, Lee, Joo Young, Kang, Han Chang, Lee, Hye Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681058/
https://www.ncbi.nlm.nih.gov/pubmed/31336576
http://dx.doi.org/10.3390/pharmaceutics11070355