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Malignant ascite-derived extracellular vesicles inhibit T cell activity by upregulating Siglec-10 expression
Background and purpose: To evade immune defense, cancer cells can employ extracellular vesicles (EVs) to inhibit the anti-tumor activity of lymphocytes in the tumor microenvironment. However, the mechanisms and key molecules that mediate the effects of EVs on lymphocytes are unclear. Patients and me...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681125/ https://www.ncbi.nlm.nih.gov/pubmed/31534365 http://dx.doi.org/10.2147/CMAR.S210568 |