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Malignant ascite-derived extracellular vesicles inhibit T cell activity by upregulating Siglec-10 expression

Background and purpose: To evade immune defense, cancer cells can employ extracellular vesicles (EVs) to inhibit the anti-tumor activity of lymphocytes in the tumor microenvironment. However, the mechanisms and key molecules that mediate the effects of EVs on lymphocytes are unclear. Patients and me...

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Detalles Bibliográficos
Autores principales: Li, Yujuan, Zhou, Jing, Zhuo, Qian, Zhang, Jingyun, Xie, Jingyan, Han, Suping, Zhao, Shuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681125/
https://www.ncbi.nlm.nih.gov/pubmed/31534365
http://dx.doi.org/10.2147/CMAR.S210568