NFATc1 deficiency in T cells protects mice from experimental autoimmune encephalomyelitis

NFATc1 is a member of the nuclear factor of activated T cells (NFAT) family of transcription factors. NFAT is activated upon T‐cell receptor activation followed by intracytoplasmatic calcium influx where calmodulin, a calcium sensor protein, activates the phosphatase calcineurin that dephosphorylate...

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Detalles Bibliográficos
Autores principales: Reppert, Sarah, Zinser, Elisabeth, Holzinger, Corinna, Sandrock, Lena, Koch, Sonja, Finotto, Susetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Immunomodulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681150/
https://www.ncbi.nlm.nih.gov/pubmed/25689841
http://dx.doi.org/10.1002/eji.201445150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681150/
https://www.ncbi.nlm.nih.gov/pubmed/25689841
http://dx.doi.org/10.1002/eji.201445150

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