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NFATc1 deficiency in T cells protects mice from experimental autoimmune encephalomyelitis

NFATc1 is a member of the nuclear factor of activated T cells (NFAT) family of transcription factors. NFAT is activated upon T‐cell receptor activation followed by intracytoplasmatic calcium influx where calmodulin, a calcium sensor protein, activates the phosphatase calcineurin that dephosphorylate...

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Detalles Bibliográficos
Autores principales:	Reppert, Sarah, Zinser, Elisabeth, Holzinger, Corinna, Sandrock, Lena, Koch, Sonja, Finotto, Susetta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Immunomodulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681150/ https://www.ncbi.nlm.nih.gov/pubmed/25689841 http://dx.doi.org/10.1002/eji.201445150

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