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Guanidinylation of Chitooligosaccharides Involving Internal Cyclization of the Guanidino Group on the Reducing End and Effect of Guanidinylation on Protein Binding Ability

In order to synthesize a promising material for developing a novel peptide/protein delivery system, guanidinylation of chitooligosaccharides with 1-amidinopyrazole hydrochloride was investigated herein. The production of guanidinylated chitooligosaccharides was demonstrated by infrared spectroscopy...

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Detalles Bibliográficos
Autores principales: Izawa, Hironori, Kinai, Mizuki, Ifuku, Shinsuke, Morimoto, Minoru, Saimoto, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681198/
https://www.ncbi.nlm.nih.gov/pubmed/31284517
http://dx.doi.org/10.3390/biom9070259