The Administration of the New Pyrimidine Derivative—4-{2-[2-(3,4-Dimethoxyphenyl)-Vinyl]-6-Ethyl-4-Oxo-5-Phenyl-4H-Pyrimidine-1-Il}Benzsulfamide Restores the Activity of Brain Cells in Experimental Chronic Traumatic Encephalopathy by Maintaining Mitochondrial Function

Background and objectives: To evaluate the effect of a new pyrimidine derivative on the change of mitochondrial function in experimental chronic traumatic encephalopathy. Materials and methods: The study was performed on male mice of the BALB/c line (acute toxicity was assessed) and male rats of the...

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Detalles Bibliográficos
Autores principales: Pozdnyakov, Dmitry I., Miroshnichenko, Kirill A., Voronkov, Andey V., Kovaleva, Tat’yana G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681389/
https://www.ncbi.nlm.nih.gov/pubmed/31319603
http://dx.doi.org/10.3390/medicina55070386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681389/
https://www.ncbi.nlm.nih.gov/pubmed/31319603
http://dx.doi.org/10.3390/medicina55070386

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