Germline deletions in the tumour suppressor gene FOCAD are associated with polyposis and colorectal cancer development

Heritable genetic variants can significantly affect the lifetime risk of developing cancer, including polyposis and colorectal cancer (CRC). Variants in genes currently known to be associated with a high risk for polyposis or CRC, however, explain only a limited number of hereditary cases. The ident...

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Detalles Bibliográficos
Autores principales: Weren, Robbert DA, Venkatachalam, Ramprasath, Cazier, Jean‐Baptiste, Farin, Henner F, Kets, C Marleen, de Voer, Richarda M, Vreede, Lilian, Verwiel, Eugène TP, van Asseldonk, Monique, Kamping, Eveline J, Kiemeney, Lambertus A, Neveling, Kornelia, Aben, Katja KH, Carvajal‐Carmona, Luis, Nagtegaal, Iris D, Schackert, Hans K, Clevers, Hans, van de Wetering, Marc, Tomlinson, Ian P, Ligtenberg, Marjolijn JL, Hoogerbrugge, Nicoline, Geurts van Kessel, Ad, Kuiper, Roland P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681464/
https://www.ncbi.nlm.nih.gov/pubmed/25712196
http://dx.doi.org/10.1002/path.4520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681464/
https://www.ncbi.nlm.nih.gov/pubmed/25712196
http://dx.doi.org/10.1002/path.4520

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