Cargando…

NAD(+)‐Dependent Enzymatic Route for the Epimerization of Hydroxysteroids

Epimerization of cholic and chenodeoxycholic acid (CA and CDCA, respectively) is a notable conversion for the production of ursodeoxycholic acid (UDCA). Two enantiocomplementary hydroxysteroid dehydrogenases (7α‐ and 7β‐HSDHs) can carry out this transformation fully selectively by specific oxidation...

Descripción completa

Detalles Bibliográficos
Autores principales: Tonin, Fabio, Otten, Linda G., Arends, Isabel W. C. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681466/
https://www.ncbi.nlm.nih.gov/pubmed/30265441
http://dx.doi.org/10.1002/cssc.201801862