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NAD(+)‐Dependent Enzymatic Route for the Epimerization of Hydroxysteroids

Epimerization of cholic and chenodeoxycholic acid (CA and CDCA, respectively) is a notable conversion for the production of ursodeoxycholic acid (UDCA). Two enantiocomplementary hydroxysteroid dehydrogenases (7α‐ and 7β‐HSDHs) can carry out this transformation fully selectively by specific oxidation...

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Detalles Bibliográficos
Autores principales: Tonin, Fabio, Otten, Linda G., Arends, Isabel W. C. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681466/
https://www.ncbi.nlm.nih.gov/pubmed/30265441
http://dx.doi.org/10.1002/cssc.201801862

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