Cardiomyocyte orientation modulated by the Numb family proteins–N-cadherin axis is essential for ventricular wall morphogenesis

The roles of cellular orientation during trabecular and ventricular wall morphogenesis are unknown, and so are the underlying mechanisms that regulate cellular orientation. Myocardial-specific Numb and Numblike double-knockout (MDKO) hearts display a variety of defects, including in cellular orienta...

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Detalles Bibliográficos
Autores principales: Miao, Lianjie, Li, Jingjing, Li, Jian, Lu, Yangyang, Shieh, David, Mazurkiewicz, Joseph E., Barroso, Margarida, Schwarz, John J., Xin, Hong-Bo, Singer, Harold A., Vincent, Peter A., Zhong, Weimin, Radice, Glenn L., Wan, Leo Q., Fan, Zhen-Chuan, Huang, Guoying, Wu, Mingfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681736/
https://www.ncbi.nlm.nih.gov/pubmed/31300538
http://dx.doi.org/10.1073/pnas.1904684116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681736/
https://www.ncbi.nlm.nih.gov/pubmed/31300538
http://dx.doi.org/10.1073/pnas.1904684116

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