Site-specific phosphorylation of myosin binding protein-C coordinates thin and thick filament activation in cardiac muscle

The heart’s response to varying demands of the body is regulated by signaling pathways that activate protein kinases which phosphorylate sarcomeric proteins. Although phosphorylation of cardiac myosin binding protein-C (cMyBP-C) has been recognized as a key regulator of myocardial contractility, lit...

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Detalles Bibliográficos
Autores principales: Ponnam, Saraswathi, Sevrieva, Ivanka, Sun, Yin-Biao, Irving, Malcolm, Kampourakis, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681757/
https://www.ncbi.nlm.nih.gov/pubmed/31308242
http://dx.doi.org/10.1073/pnas.1903033116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681757/
https://www.ncbi.nlm.nih.gov/pubmed/31308242
http://dx.doi.org/10.1073/pnas.1903033116

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