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Site-specific phosphorylation of myosin binding protein-C coordinates thin and thick filament activation in cardiac muscle
The heart’s response to varying demands of the body is regulated by signaling pathways that activate protein kinases which phosphorylate sarcomeric proteins. Although phosphorylation of cardiac myosin binding protein-C (cMyBP-C) has been recognized as a key regulator of myocardial contractility, lit...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681757/ https://www.ncbi.nlm.nih.gov/pubmed/31308242 http://dx.doi.org/10.1073/pnas.1903033116 |