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Inflammatory signaling in genomically instable cancers

Recent studies have shown that genomic instability in tumor cells leads to activation of inflammatory signaling through the cGAS/STING pathway. In this review, we describe multiple ways by which genomic instability leads to cGAS/STING-mediated inflammatory signaling, as well as the consequences for...

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Detalles Bibliográficos
Autores principales: Talens, Francien, Van Vugt, Marcel A.T.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681777/
https://www.ncbi.nlm.nih.gov/pubmed/31260383
http://dx.doi.org/10.1080/15384101.2019.1638192