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Inflammatory signaling in genomically instable cancers
Recent studies have shown that genomic instability in tumor cells leads to activation of inflammatory signaling through the cGAS/STING pathway. In this review, we describe multiple ways by which genomic instability leads to cGAS/STING-mediated inflammatory signaling, as well as the consequences for...
Autores principales: | Talens, Francien, Van Vugt, Marcel A.T.M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681777/ https://www.ncbi.nlm.nih.gov/pubmed/31260383 http://dx.doi.org/10.1080/15384101.2019.1638192 |
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