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Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of rats

Cytochrome P450s (CYPs) are phase-I metabolic enzymes playing important roles in drug metabolism, dietary chemicals and endogenous molecules. Age is a key factor influencing P450s expression. Thus, age-related changes of CYP 1–4 families and bile acid homeostasis-related CYPs, the corresponding nucl...

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Detalles Bibliográficos
Autores principales: Xu, Shang-Fu, Hu, An-Ling, Xie, Lu, Liu, Jia-Jia, Wu, Qin, Liu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681801/
https://www.ncbi.nlm.nih.gov/pubmed/31396457
http://dx.doi.org/10.7717/peerj.7429