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Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of rats
Cytochrome P450s (CYPs) are phase-I metabolic enzymes playing important roles in drug metabolism, dietary chemicals and endogenous molecules. Age is a key factor influencing P450s expression. Thus, age-related changes of CYP 1–4 families and bile acid homeostasis-related CYPs, the corresponding nucl...
Autores principales: | Xu, Shang-Fu, Hu, An-Ling, Xie, Lu, Liu, Jia-Jia, Wu, Qin, Liu, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681801/ https://www.ncbi.nlm.nih.gov/pubmed/31396457 http://dx.doi.org/10.7717/peerj.7429 |
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