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Tumour infiltrating lymphocytes and immune-related genes as predictors of outcome in pancreatic adenocarcinoma

BACKGROUND: We investigated the correlation between pancreatic ductal adenocarcinoma patient prognosis and the presence of tumour infiltrating lymphocytes and expression of 521 immune system genes. METHODS: Intratumoural CD3+, CD8+, and CD20+ lymphocytes were examined by immunohistochemistry in 12 P...

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Detalles Bibliográficos
Autores principales: D’Angelo, Alberto, Sobhani, Navid, Roviello, Giandomenico, Bagby, Stefan, Bonazza, Deborah, Bottin, Cristina, Giudici, Fabiola, Zanconati, Fabrizio, De Manzini, Nicolo, Guglielmi, Alessandra, Generali, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681957/
https://www.ncbi.nlm.nih.gov/pubmed/31381571
http://dx.doi.org/10.1371/journal.pone.0219566