Naphthalimide-Based Template for Inhibitor Screening via Cross-Linking and In-Gel Fluorescence: A Case Study against HCA II

[Image: see text] We describe a rapid electrophoresis-based method for profiling of carbonic anhydrase inhibitors. In addition to the pharmacophore moiety intended for reversible interaction with a target enzyme, a fluorescent template with a built-in azide group for photoaffinity labeling is also i...

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Detalles Bibliográficos
Autores principales: Singha, Monisha, Roy, Sayantani, Moirangthem, Ravina, Das, Amit K., Basak, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681978/
https://www.ncbi.nlm.nih.gov/pubmed/31460302
http://dx.doi.org/10.1021/acsomega.9b01044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681978/
https://www.ncbi.nlm.nih.gov/pubmed/31460302
http://dx.doi.org/10.1021/acsomega.9b01044

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