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Naphthalimide-Based Template for Inhibitor Screening via Cross-Linking and In-Gel Fluorescence: A Case Study against HCA II

[Image: see text] We describe a rapid electrophoresis-based method for profiling of carbonic anhydrase inhibitors. In addition to the pharmacophore moiety intended for reversible interaction with a target enzyme, a fluorescent template with a built-in azide group for photoaffinity labeling is also i...

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Detalles Bibliográficos
Autores principales:	Singha, Monisha, Roy, Sayantani, Moirangthem, Ravina, Das, Amit K., Basak, Amit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681978/ https://www.ncbi.nlm.nih.gov/pubmed/31460302 http://dx.doi.org/10.1021/acsomega.9b01044

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