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Plasmid DNA Mono-Ion Complex for in Vivo Sustainable Gene Expression

[Image: see text] To cleave biocompatible poly(ethylene glycol) (PEG) from the mono-ion complex (MIC) for sustainable cellular uptake in vivo, ω-amide-pentylimidazolium end-modified PEG with an ester bond, that is, APe-Im-E-PEG, has been synthesized. The hydrolysis of the resulting APe-Im-E-PEG proc...

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Detalles Bibliográficos
Autores principales: Kobayashi, Yuki, Taneichi, Sakura, Kawakami, Hiroyoshi, Negishi, Yoichi, Asayama, Shoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681980/
https://www.ncbi.nlm.nih.gov/pubmed/31460251
http://dx.doi.org/10.1021/acsomega.9b01323