Repurposing of Tranilast for Potential Neuropathic Pain Treatment by Inhibition of Sepiapterin Reductase in the BH(4) Pathway

[Image: see text] Tetrahydrobiopterin (BH(4)) is a cofactor in the production of various signaling molecules including nitric oxide, dopamine, adrenaline, and noradrenaline. BH(4) levels are critical for processes associated with cardiovascular function, inflammation, mood, pain, and neurotransmissi...

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Detalles Bibliográficos
Autores principales: Moore, Benjamin J. R., Islam, Barira, Ward, Sean, Jackson, Olivia, Armitage, Rebecca, Blackburn, Jack, Haider, Shozeb, McHugh, Patrick C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682008/
https://www.ncbi.nlm.nih.gov/pubmed/31460307
http://dx.doi.org/10.1021/acsomega.9b01228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682008/
https://www.ncbi.nlm.nih.gov/pubmed/31460307
http://dx.doi.org/10.1021/acsomega.9b01228

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