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Repurposing of Tranilast for Potential Neuropathic Pain Treatment by Inhibition of Sepiapterin Reductase in the BH(4) Pathway

[Image: see text] Tetrahydrobiopterin (BH(4)) is a cofactor in the production of various signaling molecules including nitric oxide, dopamine, adrenaline, and noradrenaline. BH(4) levels are critical for processes associated with cardiovascular function, inflammation, mood, pain, and neurotransmissi...

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Detalles Bibliográficos
Autores principales:	Moore, Benjamin J. R., Islam, Barira, Ward, Sean, Jackson, Olivia, Armitage, Rebecca, Blackburn, Jack, Haider, Shozeb, McHugh, Patrick C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682008/ https://www.ncbi.nlm.nih.gov/pubmed/31460307 http://dx.doi.org/10.1021/acsomega.9b01228

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