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Structural Basis and Mechanism for Vindoline Dimers Interacting with α,β-Tubulin

[Image: see text] Vinblastine and its derivatives used in clinics as antitumor drugs often cause drug resistance and some serious side effects; thus, it is necessary to study new vinblastine analogues with strong anticancer cytotoxicity and low toxicity. We designed a dimer molecule using two vindol...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhengqiong, Lu, Chengqi, Wang, Pei, Li, Aijing, Zhang, Hongbo, Xu, Sichuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682054/ https://www.ncbi.nlm.nih.gov/pubmed/31460305 http://dx.doi.org/10.1021/acsomega.9b00947

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