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Symmetric Anti-HCV Agents: Synthesis, Antiviral Properties, and Conformational Aspects of Core Scaffolds

[Image: see text] As hepatitis C virus (HCV) is one of the major health problems in many countries, interest has been aroused in the design, synthesis, and optimization of novel NS5A inhibitors, outside the chemical space of currently available direct acting antivirals (DAAs). Two series of symmetri...

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Detalles Bibliográficos
Autores principales: Leila, Alaa R. S., Mousa, Mai H. A., Frakolaki, Efseveia, Vassilaki, Niki, Bartenschlager, Ralf, Zoidis, Grigoris, Abdel-Halim, Mohammad, Abadi, Ashraf H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682128/
https://www.ncbi.nlm.nih.gov/pubmed/31460249
http://dx.doi.org/10.1021/acsomega.9b01242