Taar1 gene variants have a causal role in methamphetamine intake and response and interact with Oprm1

We identified a locus on mouse chromosome 10 that accounts for 60% of the genetic variance in methamphetamine intake in mice selectively bred for high versus low methamphetamine consumption. We nominated the trace amine-associated receptor 1 gene, Taar1, as the strongest candidate and identified reg...

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Detalles Bibliográficos
Autores principales: Stafford, Alexandra M, Reed, Cheryl, Baba, Harue, Walter, Nicole AR, Mootz, John RK, Williams, Robert W, Neve, Kim A, Fedorov, Lev M, Janowsky, Aaron J, Phillips, Tamara J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682400/
https://www.ncbi.nlm.nih.gov/pubmed/31274109
http://dx.doi.org/10.7554/eLife.46472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682400/
https://www.ncbi.nlm.nih.gov/pubmed/31274109
http://dx.doi.org/10.7554/eLife.46472

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