Cargando…
Immune system development and age-dependent maintenance in Klotho-hypomorphic mice
Circulating Klotho peptide hormone has anti-aging activity and affects tissue maintenance. Hypomorphic mutant Klotho [kl/kl] mice on C57BL/6xC3H, BALB/c and 129 genetic backgrounds, show decreased Klotho expression that correlate with accelerated aging including pre-mature death due to abnormally hi...
Autores principales: | Zhu, Wandi Sandra, Naler, Lynette, Maul, Robert W., Sallin, Michelle A., Sen, Jyoti Misra |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682518/ https://www.ncbi.nlm.nih.gov/pubmed/31386628 http://dx.doi.org/10.18632/aging.102121 |
Ejemplares similares
-
Noncoding variations in Cyp24a1 gene are associated with Klotho‐mediated aging phenotypes in different strains of mice
por: Singh, Amit, et al.
Publicado: (2019) -
Phenotypes of Klotho
por: Sen, Jyoti Misra
Publicado: (2019) -
Therapeutic Interference With Vascular Calcification—Lessons From Klotho-Hypomorphic Mice and Beyond
por: Lang, Florian, et al.
Publicado: (2018) -
1,25(OH)(2)D(3) dependent overt hyperactivity phenotype in klotho-hypomorphic mice
por: Leibrock, Christina B., et al.
Publicado: (2016) -
Impact of Ninjin’yoeito on frailty and short life in klotho-hypomorphic (kl/kl) mice
por: Amitani, Haruka, et al.
Publicado: (2022)