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Genetic polymorphisms and transcription profiles associated with intracranial aneurysm: a key role for NOTCH3

Intracranial aneurysm (IA) incidence is about 1~2%. However, the specific mechanisms of IA onset and development need further study. Our objective was to discover novel IA-related genes to determine possible etiologies further. We performed next-generation sequencing on nineteen Chinese patients wit...

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Detalles Bibliográficos
Autores principales: Li, Mengqi, Dong, Xinlong, Chen, Shi, Wang, Weihan, Yang, Chao, Li, Bochuan, Liang, Degang, Yang, Weidong, Liu, Xiaozhi, Yang, Xinyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682524/
https://www.ncbi.nlm.nih.gov/pubmed/31339861
http://dx.doi.org/10.18632/aging.102111