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Blood autophagy defect causes accelerated non-hematopoietic organ aging

Autophagy has been well studied in regulating aging; however, the impact of autophagy in one organ on the aging of other organs has not been documented. In this study, we used a mouse model with deletion of an autophagy-essential gene Atg7 in hematopoietic system to evaluate the intrinsic role of he...

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Detalles Bibliográficos
Autores principales: Fang, Yixuan, Zhu, Lingjiang, An, Ni, Jiang, Gaoyue, Qian, Jiawei, Zhao, Ruijin, Yuan, Na, Zhang, Suping, Wang, Jianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682532/
https://www.ncbi.nlm.nih.gov/pubmed/31327762
http://dx.doi.org/10.18632/aging.102086