Deprivation of Muscleblind-Like Proteins Causes Deficits in Cortical Neuron Distribution and Morphological Changes in Dendritic Spines and Postsynaptic Densities

Myotonic dystrophy (Dystrophia Myotonica; DM) is the most common adult-onset muscular dystrophy and its brain symptoms seriously affect patients’ quality of life. It is caused by extended (CTG)(n) expansions at 3′-UTR of DMPK gene (DM type 1, DM1) or (CCTG)(n) repeats in the intron 1 of CNBP gene (D...

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Detalles Bibliográficos
Autores principales: Lee, Kuang-Yung, Chang, Ho-Ching, Seah, Carol, Lee, Li-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682673/
https://www.ncbi.nlm.nih.gov/pubmed/31417371
http://dx.doi.org/10.3389/fnana.2019.00075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682673/
https://www.ncbi.nlm.nih.gov/pubmed/31417371
http://dx.doi.org/10.3389/fnana.2019.00075

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