COX-2 Inhibition by Diclofenac Is Associated With Decreased Apoptosis and Lesion Area After Experimental Focal Penetrating Traumatic Brain Injury in Rats

Traumatic brain injury (TBI) is followed by a secondary inflammation in the brain. The inflammatory response includes prostanoid synthesis by the inducible enzyme cyclooxygenase-2 (COX-2). Inhibition of COX-2 is associated with improved functional outcome in experimental TBI models, although central...

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Detalles Bibliográficos
Autores principales: Dehlaghi Jadid, Kayvan, Davidsson, Johan, Lidin, Erik, Hånell, Anders, Angéria, Maria, Mathiesen, Tiit, Risling, Mårten, Günther, Mattias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682700/
https://www.ncbi.nlm.nih.gov/pubmed/31417487
http://dx.doi.org/10.3389/fneur.2019.00811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682700/
https://www.ncbi.nlm.nih.gov/pubmed/31417487
http://dx.doi.org/10.3389/fneur.2019.00811

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