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CIITA-Driven MHC Class II Expressing Tumor Cells as Antigen Presenting Cell Performers: Toward the Construction of an Optimal Anti-tumor Vaccine

Construction of an optimal vaccine against tumors relies on the availability of appropriate tumor-specific antigens capable to stimulate CD4+ T helper cells (TH) and CD8+ cytolytic T cells (CTL). CTL are considered the major effectors of the anti-tumor adaptive immune response as they recognize anti...

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Detalles Bibliográficos
Autores principales: Accolla, Roberto S., Ramia, Elise, Tedeschi, Alessandra, Forlani, Greta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682709/
https://www.ncbi.nlm.nih.gov/pubmed/31417570
http://dx.doi.org/10.3389/fimmu.2019.01806