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The Role of Mitochondria in Sex-Dependent Differences in Hepatic Steatosis and Oxidative Stress in Response to Cafeteria Diet-Induced Obesity in Mice

Female mice fed a cafeteria diet (FCaf) develop higher liver steatosis and oxidative stress than males (MCaf) as a consequence of unresolved ER stress. Here, we investigated whether mitochondria play a role in this sex difference. The isolated mitochondria from FCaf showed more signs of oxidative st...

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Detalles Bibliográficos
Autores principales: Morais Mewes, Juliana, Rodrigues Silva Gasparin, Fabiana, Yoshida, Tiago, Amâncio Daniel da Silva, Mariana, Raquel Marçal Natali, Maria, Francisco Veiga Bizerra, Paulo, Sayuri Utsunomiya, Karina, Hideo Gilglioni, Eduardo, Shigueaki Mito, Marcio, Cristiane Mantovanelli, Gislaine, Thais Lima de Souza, Byanca, Makiyama Klosowski, Eduardo, Luiza Ishii-Iwamoto, Emy, Constantin, Jorgete, Polimeni Constantin, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682896/
https://www.ncbi.nlm.nih.gov/pubmed/31315289
http://dx.doi.org/10.3390/nu11071618