Lupin Peptide T9 (GQEQSHQDEGVIVR) Modulates the Mutant PCSK9(D374Y) Pathway: in vitro Characterization of its Dual Hypocholesterolemic Behavior

GQEQSHQDEGVIVR (T9) is a peptide originated by the tryptic digestion of lupin β-conglutin that is absorbed in human intestinal Caco-2 cells. A previous study has shown that T9 impairs the protein–protein interaction between mutant D374Y Proprotein Convertase Subtilisin/Kexin 9 (PCSK9(D374Y)) and the...

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Detalles Bibliográficos
Autores principales: Lammi, Carmen, Bollati, Carlotta, Lecca, Davide, Abbracchio, Maria Pia, Arnoldi, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683083/
https://www.ncbi.nlm.nih.gov/pubmed/31330826
http://dx.doi.org/10.3390/nu11071665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683083/
https://www.ncbi.nlm.nih.gov/pubmed/31330826
http://dx.doi.org/10.3390/nu11071665

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