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O-cyclic phytosphingosine-1-phosphate stimulates HIF1α-dependent glycolytic reprogramming to enhance the therapeutic potential of mesenchymal stem cells

O-cyclic phytosphingosine-1-phosphate (cP1P) is a novel chemically synthesized sphingosine metabolite derived from phytosphingosine-1-phosphate. Although structurally similar to sphingosine-1-phosphate (S1P), its biological properties in stem cells remain to be reported. We investigated the effect o...

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Detalles Bibliográficos
Autores principales: Lee, Hyun Jik, Jung, Young Hyun, Choi, Gee Euhn, Kim, Jun Sung, Chae, Chang Woo, Lim, Jae Ryong, Kim, Seo Yihl, Lee, Joo Eun, Park, Min Chul, Yoon, Jee Hyeon, Choi, Myeong Jun, Kim, Kye-Seong, Han, Ho Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683124/
https://www.ncbi.nlm.nih.gov/pubmed/31383843
http://dx.doi.org/10.1038/s41419-019-1823-7