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Spatially conserved motifs in complement control protein domains determine functionality in regulators of complement activation-family proteins
Regulation of complement activation in the host cells is mediated primarily by the regulators of complement activation (RCA) family proteins that are formed by tandemly repeating complement control protein (CCP) domains. Functional annotation of these proteins, however, is challenging as contiguous...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683126/ https://www.ncbi.nlm.nih.gov/pubmed/31396570 http://dx.doi.org/10.1038/s42003-019-0529-9 |