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Spatially conserved motifs in complement control protein domains determine functionality in regulators of complement activation-family proteins

Regulation of complement activation in the host cells is mediated primarily by the regulators of complement activation (RCA) family proteins that are formed by tandemly repeating complement control protein (CCP) domains. Functional annotation of these proteins, however, is challenging as contiguous...

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Detalles Bibliográficos
Autores principales: Ojha, Hina, Ghosh, Payel, Singh Panwar, Hemendra, Shende, Rajashri, Gondane, Aishwarya, Mande, Shekhar C., Sahu, Arvind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683126/
https://www.ncbi.nlm.nih.gov/pubmed/31396570
http://dx.doi.org/10.1038/s42003-019-0529-9

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