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Iron accumulation in tumor-associated macrophages marks an improved overall survival in patients with lung adenocarcinoma

Iron-loaded tumor-associated macrophages (iTAMs) show a pro-inflammatory phenotype, hallmarked by anti-tumorigenic activity and an ability to attenuate tumor growth. Here we explored the relevance of these findings in lung cancer patients by investigating the impact of the iTAM content in the tumor...

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Detalles Bibliográficos
Autores principales: Thielmann, Carl Maximilian, Costa da Silva, Milene, Muley, Thomas, Meister, Michael, Herpel, Esther, Muckenthaler, Martina U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683135/
https://www.ncbi.nlm.nih.gov/pubmed/31383898
http://dx.doi.org/10.1038/s41598-019-47833-x